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Monocarboxyl Dextran (500 kDa)
- n° Art.:DEX1110
- Storage temperature:RT
- Masse moléculaire:500000 Da
from 475,00 €
description
Monofunctionalized dextrans carrying a single functional group on the end of the polymer. These monofunctionalized dextrans can be used much like PEG-it can be used to increase protein half-life, reduce immunogenicity, and passivate surfaces.
The dextran main chain is alpha-1,6-glucose with about 5% alpha-1,3-branching.
references
Drug delivery with a pH-sensitive star-like dextran-graft polyacrylamide copolymer; A. Grebinyk, S. Prylutska, S. Grebinyk, S. Ponomarenko, P. Virych, V. Chumachenko, N. Kutsevol, Y. Prylutskyy, U. Ritter, M. Frohme; Nanoscale Adv. 2022; 4: 507-5088. https://doi.org/10.1039/D2NA00353H
Dextran conjugates in drug delivery; J. Varshosaz; Expert Opinion on Drug Delivery 2012; 9(5): 509-523. https://doi.org/10.1517/17425247.2012.673580
Chapter 12 - Dextran-based nanomaterials in drug delivery applications; S. Maity, S. Saha, S. Sarkar, P. Kumar, A. Kumar Gautam, A. Bharti Sonkar; Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications 2021; 293-312. https://doi.org/10.1016/B978-0-12-820874-8.00019-1
Recent advances in dextran-based drug delivery systems: From fabrication strategies to applications; Q. Hu, Y. Lu, Y. Luo; Carbohydrate Polymers 2021; 264: 117999. https://doi.org/10.1016/j.carbpol.2021.117999
Preparation and drug delivery of dextran-drug complex; S. Huang, G. Huang; Drug Deliv. 2019; 26(1): 252-261. https://doi.org/10.1080/10717544.2019.1580322
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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