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Fmoc-L-Thz(Me2)-OH
Nom chimique: (R)-N-(9-Fluorenylmethyloxycarbonyl)-2,2-dimethyl-thiazolidine-4-carboxylic acid // Synonymes: Fmoc-Thz(Me2)-OH, Fmoc-Cys(PsiMe,MePro)-OH, Fmoc-Cys(PsiMe,MePro), Fmoc-Cysteine Pseudoproline
- n° Art.:FAA1437
- n° CAS:873842-06-9
- Formule:C21H21NO4S
- Storage temperature:2-8°C
- Masse moléculaire:383,46 g/mol
- Pureté:min. 99%
- Pureté Énantiomérique:min. 99,7%
from 125,00 €
description
A cysteine pseudoproline with short deprotection times in TFA. Deprotected procedure: Dry resin (5 mg) was treated with TFA/TIS/H2O (95:2.5:2.5) for several hours at rt. The cleavage mixture was evaporated with a stream of argon, precipitated with Et2O, centrifuged and the pellet was redissolved in H2O/CH3CN (1:1) for analysis by HPLC and LCMS. The deprotection time and temperature is sequence-dependent.
references
Cysteine Pseudoprolines for Thiol Protection and Peptide Macrocyclization Enhancement in Fmoc-Based Solid-Phase Peptide Synthesis. Tobias M. Postma, Fernando Albericio; Org. Lett. 2014; 16(6): 1772-1775. DOI: 10.1021/ol5004725
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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