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Fmoc-D-Thr[Psi(Me,Me)Pro]-OH
Nom chimique: (4R,5S)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid
- n° Art.:PSI1650
- n° CAS:159681-93-3
- Formule:C22H23NO5
- Storage temperature:2-8°C
- Masse moléculaire:381,43 g/mol
- Pureté:min.99%
from 95,00 €
description
D-Threonine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids.
references
Solid-Phase Synthesis of an “Inaccessible” hGH-Derived Peptide Using a Pseudoproline Monomer and SIT-Protection for Cysteine; S. R. Manne, A. Chakraborty, K. Rustler, T. Bruckdorfer, B. G. de la Torre, F. Albericio; ACS Omega 2022; 7(32): 28487–28492. https://doi.org/10.1021/acsomega.2c03261
Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis; D. A. Senko, N. D. Timofeev, I. E. Kasheverov, I. A. Ivanov; Amino Acids 2021; 53: 665–671. https://doi.org/10.1007/s00726-021-02973-1
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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