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Fmoc-L-Glu(EDANS)-OH
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-5-(2-(5-sulfonaphthalen-1-ylamino)ethylamido)-L-glutamic acid // Synonymes: Fmoc-Glu(EDANS)-OH, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-oxo-5-(2-(5-sulfonaphthalen-1-ylamino)ethylamino)pentanoic acid,N-alpha-(9-Fluorenylmethyloxycarbonyl)-5-{[(2'-aminoethyl)-amino ]naphthelenesulfonic acid}-L-glutamic acid
- n° Art.:FAA4410
- n° CAS:193475-66-0
- Formule:C32H31N3O8S
- Storage temperature:2-8°C
- Masse moléculaire:617,67 g/mol
from 170,00 €
description
Building block for the SPPS of internally quenched fluorogenic peptide substrates (FRET substrates). The fluorescent group EDANS can be efficiently quenched by the non-fluorescent DABCYL chromophore (introduced by Fmoc-Lys(Dabcyl)-OH (FAA1498).
references
J.W. Drijfhout et al., Proceedings of the 14th American Peptide Symposium, p. 129, P.T.P. Kaumaya and R.S. Hodges, eds., Mayflower Scientific Ltd. England, (1996).
A general method for the preparation of internally quenched fluorogenic protease substrates using solid-phase peptide synthesis. Maggiora L.L., Smith C.W., Zhang Z.Y.; J. Med. Chem. 1992; 35(21): 3727-30.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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