Fmoc-L-Argpyrimidine(Pbf,TBMS)-OH

Nom chimique: (S)-2-(9-Fluorenylmethyloxycarbonylamino)-5-(N-(4,6-dimethyl-5-(t-butyldimethylsilyloxy)pyrimidin-2-yl)-2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)pentanoic acid // Synonymes: Fmoc-Argpyrimidine(Pbf,TBMS)-OH,(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(N-(4,6-dimethyl-5-(t-butyldimethylsilyloxy)pyrimidin-2-yl)-2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamid o)pentanoicacid; related CAS: 2147738-36-9

n° Art.:FAA5530
n° CAS:2389078-23-1
Formule:C₄₅H₅₈N₄O₈SSi
Storage temperature:-20°C
Masse moléculaire:843,11 g/mol

from Sur demande

Grouped product items
Nombre	Unité de vente	Prix	SKU	Disponibilité
Sur demande	Sur demande	Sur demande	FAA5530.0000	sur demande
Fiches de données de sécurité

Inquiry

Skip to the end of the images gallery

Skip to the beginning of the images gallery

description

Maillard reaction product (MRP) are indicators for heat treatment of food. They are used as marker of the nutritional quality of food.

Argpyrimidine is a fluorescent adduct derived from methylglyoxal and arginine residues.

references

Antioxidant properties of argpyrimidine; N. Sreejayan, X. Yang, K. Palanichamy, K. Dolence and J. Ren; Eur J Pharmacol 2008; 593: 30-5. https://doi.org/10.1016/j.ejphar.2008.07.030

Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy; R. Gomes, M. Sousa Silva, A. Quintas, C. Cordeiro, A. Freire, P. Pereira, A. Martins, E. Monteiro, E. Barroso and A. Ponces Freire; The Biochemical journal 2005; 385: 339-45. https://doi.org/10.1042/BJ20040833

Therapeutic potential of breakers of advanced glycation end product-protein crosslinks; S. Vasan, P. Foiles and H. Founds; Archives of biochemistry and biophysics 2003; 419: 89-96. https://doi.org/10.1016/j.abb.2003.08.016

N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer; M. A. Glomb, D. Rosch and R. H. Nagaraj; J Agric Food Chem 2001; 49: 366-72. https://doi.org/10.1021/jf000493r

Argpyrimidine, a blue fluorophore in human lens proteins: high levels in brunescent cataractous lenses; P. S. Padayatti, A. S. Ng, K. Uchida, M. A. Glomb and R. H. Nagaraj; Invest Ophthalmol Vis Sci 2001; 42: 1299-304.

Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts; T. Oya, N. Hattori, Y. Mizuno, S. Miyata, S. Maeda, T. Osawa and K. Uchida; J Biol Chem 1999; 274: 18492-502. https://doi.org/10.1074/jbc.274.26.18492

Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct; I. N. Shipanova, M. A. Glomb and R. H. Nagaraj; Archives of biochemistry and biophysics 1997; 344: 29-36. https://doi.org/10.1006/abbi.1997.0195

Novel modifications of Ná-boc-arginine and Ná-CBZ-lysine by methylglyoxal; Y. Al-Abed, T. Mitsuhashi, P. Ulrich and R. Bucala; Bioorganic & Medicinal Chemistry Letters 1996; 6: 1577-1578. https://doi.org/10.1016/s0960-894x(96)00276-4

Synthetic Approach to Argpyrimidine as a Tool for Investigating Nonenzymatic Posttranslational Modification of Proteins; M. Matveenko and C. F. W. Becker; Synlett 2017; 28: 1950-1955. https://doi.org/10.1055/s-0036-1588225

Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine; M. Matveenko, E. Cichero, P. Fossa and C. F. W. Becker; Ang. Chem. Int. Ed. 2016; 55: 11397-11402. https://doi.org/10.1002/anie.201605366

Random coil shifts of posttranslationally modified amino acids; A. C. Conibear, K. J. Rosengren, C. F. W. Becker and H. Kaehlig; Journal of Biomolecular NMR 2019; 73: 587-599. https://doi.org/10.1007/s10858-019-00270-4

* Disclaimer

We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.