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Fmoc-L-Lys(iNoc)-OH
Nom chimique: N-alpha-(9-Fluorenylmethoxycarbonyl)-N-epsilon-pyridylmethoxycarbonyl-L-lysine, Fmoc-L-Lys(isonicotinyloxycarbonyl)-OH // Synonymes: Fmoc-Lys(iNoc)-OH
- n° Art.:FAA8775
- n° CAS:1459694-90-6
- Formule:C28H29N3O6
- Storage temperature:2-8°C
- Masse moléculaire:503,56 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 108,00 €
description
This orthogonally side-chain protected Lysine is stable to most reagents used in peptide synthesis. The isonicotinyloxycarbonyl (iNoc)-group can be removed under mild reducing conditions like Zn/AcOH, Pd/C/H2, SmI2 in aq. DMF etc. Isomeric purity >99.9%.
references
Isonicotinyloxycarbonyl a novel amino protecting group for peptide synthesis; D. F. Veber, W. J. Paleveda, Y. C. Lee, R. Hirschmann; J. Org. Chem. 1977; 42(20): 3286-3288. https://doi.org/10.1021/jo00440a018.
Total Synthesis and Structural Characterization of Caveolin-1; H. Hojo, T. Takei, Y. Asahina, N. Okumura, T. Takao, M. So, I. Suetake, T. Sato, A. Kawamoto, Y. Hirabayashi; Angew. Chem. Int. Ed. 2021; 60(25): 13900-13905. https://doi.org/10.1002/anie.202100826.
Chemoenzymatic Synthesis of the Immunoglobulin Domain of Tim-3 Carrying a Complex-Type N-Glycan by Using a One-pot Ligation; Y. Asahina, S. Kamitori, T. Takao, N. Nishi, H. Hojo; Angew. Chem. Int. Ed. 52(37): 9733-9737. https://doi.org/10.1002/anie.201303073.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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