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N3-HABA*DCHA (2S)
Nom chimique: (S)-4-azido-2-hydroxybutyric acid dicyclohexalamine // Synonymes: Azido hydroxybutyric acid DCHA salt, (2S)-4-azido-2-hydroxybutanoic acid dicyclohexylamine, N3-HABA
- n° Art.:HAA3175
- n° CAS:959148-55-1
- Formule:C4H7N3O3*C12H23N
- Storage temperature:2-8°C
- Masse moléculaire:145,12*181,32 g/mol
- Pureté:min. 99%
- Pureté Énantiomérique:min. 99,7%
from 80,00 €
description
This azide-containing chiral alpha-hydroxybutyric acid can be used as a building block for the construction of aminoglycoside antibiotics. Further modification using Click-chemistry (CuAAC) can be performed.
references
Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations; I. Nudelman, A. Rebibo-Sabbah, M. Cherniavsky, V. Belakhov, M. Hainrichson, F. Chen, J. Schacht, D. S. Pilch, T. Ben-Yosef, and T. Baasov; J. Med. Chem. 2009; 52: 2836-2845. https://doi.org/10.1021/jm801640k.
Aminoglycoside antibiotics; F. Liu, G. Myers; 2018; WO2019079706A1
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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