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Mal-L-Dap(Boc)-OPfp
Nom chimique: N-alpha-MaleimidoN-beta-t-butyloxycarbonyl-L-2,3-diaminopropionic acid pentafluorophenolate // Synonymes: Mal-Dap(Boc)-OPfp, Mal-Dpr(Boc)-OPfp, 2,3,4,5,6-pentafluorophenyl (2S)-3-{[(tert-butoxy)carbonyl]amino}-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
- n° Art.:MAA1080
- n° CAS:1887132-90-2
- Formule:C18H15F5N2O6
- Storage temperature:2-8°C
- Masse moléculaire:450,31 g/mol
- Pureté:min. 98%
from 95,00 €
description
Mal-Dap(Boc)-OPfp is used in drug conjugate construction leading to more stable conjugates due to Dap neighboring-group assistance. This strategy is widely used in antibody-drug conjugation (ADC).
references
Lyon, Robert; Burke, Patrick; Hunter, Joshua; PCT Int. Appl. (2015), WO 2015057699 A2;
Cong, Qiang; Gangwar, Sanjeev; Rangan, Vangipuram S.; Sung, Mei-Chen; PCT Int. Appl. (2017), WO 2017196598 A1;
Burke, Patrick J.; Courter, Joel; PCT Int. Appl. (2017), WO 2017096311 A1.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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