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H-L-Cys(Clt)-2CT Resin
Nom chimique: H-L-Cys(Clt)-2-chlorotrityl resin // Synonymes: H-Cys(Clt)-2CT Resin
- n° Art.:RAA1050
- Taille des particules:100-200 mesh
- DVB réticulation:1% DVB
- Chargement:> 0.4 mmol/g
from Sur demande
description
The Clt (2-chlorotrityl) protecting group is more stable than the commonly used Trt group and is best deprotected by oxidative methods with Iodine resulting in a simultaneous disulfide bridge formation. It is therefore best used in the synthesis of cyclic peptides with several disulfide bridges in particular for the synthesis of the second S-S bridge.
references
Aletras A., Barlos K. et al; Int. J. Pept. Protein Res. 1995; 45(5): 488-496.
Barlos K. et al; Int. J. Pept. Protein Res. 1991; 38(6): 555-561.
Sarah L.M. et al, in „Fmoc Solid Phase Synthesis. A practical approach“, Ed.: Chan W.C., White P.D. Oxford University Press 2000, page 177.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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