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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
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Resins functionalized with trityl linkers are highly acid sensitive, as the three phenyl rings stabilize the benzylic carbocation that is generated during cleavage. These cleavage conditions are so mild that only 1% of TFA is needed, and even less acidic protocols using 20% hexafluoroisopropanol (HFIP) are sufficient to cleave the products from the resin. Various trityl-based linkers exist with different substitutions on the trityl group that fine-tune the cleavage conditions and stability of the preloaded resin.
