Boc-L-HAla(4-Br)-OtBu

Chemical name: N-alpha-(t-butyloxycarbonyl)-L-(4-bromo)-homoalanine tert-butyl ester // Synonyms: N-alpha-(t-butyloxycarbonyl)-L-(4-bromo)-homoalanine t-butyl ester, Boc-L-(4-bromo)-homoalanine tert-butyl ester, Boc-L-(4-bromo)-homoalanine t-butyl ester, 1,1-Dimethylethyl(2S)-4-bromo-2-[[(1,1-di methylethoxy)carbonyl]amino]butanoate, Tert-butyl

  • Product code:BAA4680
  • CAS No.:163210-89-7
  • Storage temperature:2-8°C
  • Formula:C13H24BrNO4a
  • Molecular weight:338.24 g/mol
  • Purity :min. 98%
  • Enantiomeric Purity:min. 99,7%

from €70.00

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
€70.00
BAA4680.0250
<10 business days
500 mg
€126.00
BAA4680.0500
<10 business days
1 g
€196.00
BAA4680.1000
<10 business days
5 g
€700.00
BAA4680.5000
Please inquire
25 g
€2,800.00
BAA4680.9025
Please inquire
description

This brominated azidohomoalanine building block is reported as precursor for the synthesis of hydrocarbon-bridged diaminodiacids, as functionalized linker, as well as for nucleobase peptide synthesis.


references

Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries; S. Pomplun, Z. P. Gates, G. Zhang, A. J. Quartararo, B. L. Pentelute; J. Am. Chem. Soc. 2020; 142(46): 19642-19651. https://doi.org/10.1021/jacs.0c08964.


Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state; M. J. van Haren, R. Taig, J. Kuppens, J. S. Toraño, E. E. Moret, R. B. Parsons, D. Sartini, M. Emanuelli, N. I. Martin; Org. Biomol. Chem. 2017; 15: 6656-6657. https://doi.org/10.1039/c7ob01357d.


Efficient synthesis of hydrocarbon-bridged diaminodiacids through nickel-catalyzed reductive cross-coupling; T. Wang, Y.-F. Kong, Y. Xu, J. Fan, H.-J. Xu, D. Bierer, J. Wang, J. Shi, Y.-M. Li; Tetrahedron Lett. 2017; https://doi.org/10.1016/j.tetlet.2017.09.006.

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