Fmoc-L-Asp(cHx)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-cyclohexyl ester // Synonyms: Fmoc-L-Asp(OcHx)-OH, Fmoc-Asp(cHx)-OH

  • Product code:FAA1705
  • CAS No.:130304-80-2
  • Storage temperature:2-8°C
  • Formula:C25H27NO6
  • Molecular weight:437.47 g/mol

from €150.00

Grouped product items
Qty Packing unit Price SKU Availability
5 g
€150.00
FAA1705.0005
<10 business days
25 g
€370.00
FAA1705.0025
<10 business days
description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.

references

A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. BennyGerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.

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