Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Fmoc-TOAC-OH
Chemical name: 2,2,6,6-Tetramethylpiperidine-N-oxyl-4-(9-fluorenylmethyloxycarbonyl-amino)-4-carboxylic acid // Synonyms: 2,2,6,6-Tetramethylpiperidine-N-oxyl-4-(Fmoc-amino)-4-carboxylic acid
- Product code:FAA1771
- CAS No.:93372-25-9
- Formula:C25H29N2O5
- Storage temperature:-20°C
- Molecular weight:437.52 g/mol
- Purity :min. 98%
from €120.00
description
Fmoc-TOAC is used to synthesize spin-labeled peptides for ESR studies.
It has to be noted that using solid-supported synthesis radical activity might be lost during deprotection with TFA or HF. The crude spin-labeled peptides can be submitted to alkaline treatment (pH 10, for 1 h at 50°C) for complete reversal of the N-O protonation that occurs during the HF or TFA cleavage reaction. Detailed protocols can be found: Dousset, Magali (2005): COMBINATORIAL APPROACHES TOWARDS ACTIVE MODELS FOR GALACTOSE OXIDASE. Inaugural-Dissertation. Universität zu Köln and Karim, C. B., Zhang, Z., & Thomas, D. D. Synthesis of TOAC spin-labeled proteins and reconstitution in lipid membranes. Nature Protocols (2007), 2(1), 42-49. https://doi.org/10.1038/nprot.2007.2
references
JACS 1993; 115(23): 11042-11043.
Dissertation Magali Dousset, COMBINATORIAL APPROACHES TOWARDS ACTIVE MODELS FOR GALACTOSE OXIDASE, 2005
Marchetto, Reinaldo; Schreier, Shirley; Nakaie, Clovis R. Journal of the American Chemical Society (1993), 115(23), 11042-3. DOI:10.1021/ja00076a093;
Ortony, Julia H.; Qiao, Baofu; Newcomb, Christina J.; Keller, Timothy J.; Palmer, Liam C.; Deiss-Yehiely, Elad; Olvera de la Cruz, Monica; Han, Songi; Stupp, Samuel I. Journal of the American Chemical Society (2017), 139(26), 8915-8921. DOI:10.1021/jacs.7b02969;
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
We found other products you might like!
