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Fmoc-L-Orn(N3)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-delta-azido-L-ornithine // Synonyms: N-alpha-(9-Fluorenylmethyloxycarbonyl)-delta-azido-L-norvaline, (S)-2-(9-Fluorenylmethyloxycarbonylamino)-5-azidopentanoic acid, (S)-Fmoc-2-amino-5-azido-pentanoic acid,Fmoc-L-azidoornitine, Fmoc-L- delta-azidoornithine, Fmoc-Orn(N3)-OH, Fmoc-L-Orn(
- Product code:FAA6880
- CAS No.:1097192-04-5
- Formula:C20H20N4O4
- Storage temperature:2-8°C
- Molecular weight:380.4 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,7%
from €72.00
description
Fmoc-Orn(N3) is incorporated into peptides that can be further selectively modified using Staudinger ligation or Click-chemistry.
references
Kawamoto, Steven A.; Coleska, Adriana; Ran, Xu; Yi, Han; Yang, Chao-Yie; Wang, Shaomeng Journal of Medicinal Chemistry (2012), 55(3), 1137-1146. DOI:10.1021/jm201125d;
de Araujo, Aline D.; Hoang, Huy N.; Kok, W. Mei; Diness, Frederik; Gupta, Praveer; Hill, Timothy A.; Driver, Russell W.; Price, David A.; Liras, Spiros; Fairlie, David P. Angewandte Chemie, International Edition (2014), 53(27), 6965-6969. DOI:10.1002/anie.201310245;
Holland-Nell, Kai; Meldal, Morten Angewandte Chemie, International Edition (2011), 50(22), 5204-5206.DOI:10.1002/anie.201005846;
Zavoiura, Oleksandr; Resch-Genger, Ute; Seitz, Oliver Bioconjugate Chemistry (2018), 29(5), 1690-1702. DOI:10.1021/acs.bioconjchem.8b00157;
Tala, Srinivasa R.; Singh, Anamika; Lensing, Cody J.; Schnell, Sathya M.; Freeman, Katie T.; Rocca, James R.; Haskell-Luevano, Carrie ACS Chemical Neuroscience (2018), 9(5), 1001-1013. DOI:10.1021/acschemneuro.7b00422.
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