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Fmoc-L-Thr(MsbH)-OH
Chemical name: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(bis(4-(methylsulfinyl)phenyl)methyl)-L-threonine // Synonyms: Fmoc-O-(bis(4-(methylsulfinyl)phenyl)methyl)-L-threonine, Fmoc-(MsbH) L-Thr-OH, Fmoc-(MsbH) L-Threonine,O-[bis[4-(methylsulfinyl)phenyl]methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-Threonine, O-[b is[4-(methylsulfinyl)phenyl]methyl]-N-Fmoc-L-Threo
- Product code:FAA7865
- CAS No.:2919325-58-7
- Storage temperature:2-8°C
- Formula:C34H33NO7S2
- Molecular weight:631.76 g/mol
from €600.00
description
A Fmoc protected L-Threonine for SPSS, with an MsbH protected hydroxyl group. The MsbH protecting group is removed by reduction of the sulfoxides, followed by acidolysis with TFA.
references
Solid-Phase Peptide Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme; S. Noki, E. Brasil, H. Zhang, T. Bruckdorfer, B. de la Torre, F. Albericio; J. Org. Chem. 2022; 87(15): 9443–9453. https://doi.org/10.1021/acs.joc.2c01056
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