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Fmoc-L-Nva(3-Et-3-Me)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)- 3-ethyl-3-methyl-L-norvaline // Synonyms: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-ethyl-3-methylpentanoic acid, Fmoc-3-ethyl-3-methyl-L-norvaline, Fmoc-3-ethyl-3-methyl-Nva, Fmoc-3-ethyl-3-methyl-L-Nva,Fmoc-Nva(3-Et-3-Me)-OH
- Product code:FAA8500
- CAS No.:2988300-87-2
- Formula:C23H27NO4
- Storage temperature:2-8°C
- Molecular weight:381.47 g/mol
from €800.00
description
Iris Biotech offers various Nva derivatives with different sterical and electronical properties, which can be incorporated into peptides for the investigation of structure activity relationships and lead optimization. Furthermore, Norvaline and its derivatives can be incorporated into peptides as surrogate for Methionine in order to prevent oxidation of Met.
references
Scaleable catalytic asymmetric Strecker syntheses of unnatural alpha-amino acid; S. J. Zuend, M. P. Coughlin, M. P. Lalonde, E. N. Jacobsen; Nature 2009: 461(7266): 968-70. https://doi.org/10.1038/nature08484.
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