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Fmoc-L-Lys(4-N3-Z)-OH
Chemical name: N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(((4-azidobenzyl)oxy)carbonyl)-L-lysine // Synonyms: Fmoc-Lys(4-N3-Z)-OH, Fmoc-Lys(Z(4-N3))-OH, Fmoc-pAzZLys, Fmoc-Lys(Z-4-N3)-OH,(2S)-6-({[(4-azidophenyl)methoxy]carbonyl}amino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid,(2S)-6-(4-A zido-benzyloxycarbonylamino)-2-(9H-fluoren-9-ylmet
- Product code:FAA8830
- CAS No.:1446511-14-3
- Storage temperature:2-8°C
- Formula:C29H29N5O6
- Molecular weight:543.58 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,7%
from €90.00
description
Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition.
references
References:
A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells; Y. Ge, X. Fan, P. R. Chen; Chem. Sci. 2016; 7: 7055-7060. https://doi.org/10.1039/C6SC02615J
Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation; J. S. Wesalo, J. Luo, K. Morihiro, J. Liu, A. Deiters; ChemBioChem 2020; 21: 141-148. https://doi.org/10.1002/cbic.201900464
WO2013100132A1
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