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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-t-butylester-N’-(2,4-dimethoxybenzyl)-glycine // Synonyms: (S)-N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-N-(2,4-dimethoxybenzyl)glycine,N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-a-aspartyl-N-[(2,4-dimethoxyphenyl)methyl]gl ycine 1-(1,1-dimethylethyl)ester,(S)-2-(2-((((9H-F
from €790.00
2,4-Dimethoxybenzyl (Dmb) and 2,4,6-trimethoxybenzyl (Tmb) - used for temporary protection of the amide nitrogen of a peptide bond - prevent aggregation during solid phase synthesis. They can also increase peptide cyclization efficiency. Glycine building blocks are available as Fmoc-DmbGly-OH (FAA3390) and Fmoc-TmbGly-OH (FAA3400). For ease of synthesis a dipeptide building block can be used, in order to couple with one process two amino acids. Acidic deprotection methods as normally applied on Wang resin generate the native sequence.
N,O-bisFmoc derivatives of N-(2-hydroxy-4-methoxybenzyl)-amino acids: Useful intermediates in peptide synthesis; T. Johnson, M. Quibell, R. C. Sheppard; J. Pept. Sci. 1995; 1(1): 11-25. https://doi.org/10.1002/psc.310010104
Innovation and perspectives in solid phase synthesis: peptides, proteins and nucleic acids, biological and biomedical applications; J. F. Kennedy, C. J. Knill; edited by R. Epton; Mayflower Scientific Ltd 1995; 71. https://doi.org/10.1002/pi.1995.210380416
Proceeding of the 24th EPS; K. Jauch et al; edited by R. Ramage, R. Epton; Mayflower Scientific Ltd 1996; 497.
All-L-Leu-Pro-Leu-Pro: a challenging cyclization; M. El Haddadi, F. Cavelier, E. Vives, A. Azmani, J. Verducci, J. Martinez; J. Pept. Sci. 2000; 6(11): 560-570. https://doi.org/10.1002/1099-1387(200011)6:11<560::AID-PSC275>3.0.CO;2-I
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