H-L-His(2-Thio)-OH

Chemical name: (S)-2-amino-3-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acid // Synonyms: H-2-Thio-L-Histidine, Thiohistidine, H-His(2-Thio)-OH

  • Product code:HAA9290
  • CAS No.:2002-22-4
  • Storage temperature:2-8°C
  • Formula:C6H9N3O2S
  • Molecular weight:187.22 g/mol

from €150.00

Grouped product items
Qty Packing unit Price SKU Availability
100 mg
€150.00
HAA9290.0100
<10 business days
250 mg
€300.00
HAA9290.0250
<10 business days
1 g
€900.00
HAA9290.1000
<10 business days
description

An analogue of ergothioneine, which can be incorporated into peptides to increase the antioxidant capacity of the peptide.


references

Short protecting-group-free synthesis of 5-acetylsulfanyl-histidines in water: novel precursors of 5-sulfanyl-histidine and its analogues; Org. Biomol. Chem. 2016; 14: 10473-10480. https://doi.org/10.1039/C6OB01870J.


Improved synthesis of the super antioxidant, ergothioneine, and its biosynthetic pathway intermediates; P. L. Khonde, A. Jardine; Org. Biomol. Chem. 2015; 13: 1415-1419. https://doi.org/10.1039/C4OB02023E.


Cysteine as a suitable sulfur reagent for the protecting-group-free synthesis of sulfur-containing amino acids: biomimetic synthesis of L-ergothioneine in water; I. Erdelmeier, S. Daunay, R. Lebel, L. Farescour, J.-C. Yadan; Green Chem. 2012; 14: 2256-2265. https://doi.org/10.1039/C2GC35367A.


Role of 2-oxo and 2-thioxo modifications on the fragmentation reactions of histidine radical cation; Rapid Commun. Mass Spectrom. 2011; 25: 251-261.

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