Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Z-DEVD-Rh110-p
Chemical name: N-Benzyloxycarbonyl-aspartyl-glutamyl-valyl-aspartyl-Rh110-D-proline // Synonyms: Z-Asp-Glu-Val-Asp-Rhodamine(110)-D-Pro, substrate for caspase-3
- Product code:LS-3550
- Formula:C51H53N7O16
- Storage temperature:-20°C
- Molecular weight:1020.02 g/mol
from €1,210.00
description
This asymmetric Rhodamine 110 substrates for caspase-3 employs a simple and straight forward kinetics upon analysis. Absorption wave length 492 nm, emission wave length 529 nm. While the intact substrate is virtually non-fluorescent, fluorescence largely increases (approx.. 3500 fold) upon cleavage. Superior signal-to-noise ratio combined with high sensitivity. In Rh110 assays this substrate delivers much less false positive hits in synthetic product libraries than corresponding AMC (7-amino-4-methylcoumarin) substrates.
references
Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin; Farid El Oualid, Remco Merkx, Reggy Ekkebus, Dharjath S. Hameed, Judith J. Smit, Annemieke de Jong, Henk Hilkmann, Titia K. Sixma, and Huib Ovaa; Angew. Chem. Int. Ed. 2010; 49: 10149 -10153. DOI: 10.1002/anie.201005995.
C. Wiesmann et al.; J. Mol. Biol. 2012; 419: 4-21.
S.K. Grant et al.; J. Biomol. Screen. 2002; 7(6): 531-540.
U. Hassiepen et al.; Anal. Biochem. 2007; 371: 201-207.
S.P. Leytus et al.; Biochem. J. 1983; 209: 299-307.
S.P. Leytus et al.; Biochem. J. 1983; 209: 299-307.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
Brochures & Flyers
We found other products you might like!
