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Palm-L-Glu-OtBu
Chemical name: N-alpha-Palmitoyl-L-glutamic-acid alpha-t-butyl ester // Synonyms: Palm-Glu-OtBu, Palmitoyl-Glu-OtBu, Palmitoyl-L-Glu-OtBu, (S)-t-butyl 2-palmitamidopentanoate, (S)-5-t-butoxy-5-oxo-4-palmitamidopentanoic acid
- Product code:PAA1160
- CAS No.:536721-25-2
- Formula:C25H47NO5
- Storage temperature:2-8°C
- Molecular weight:441.64 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,7%
from €84.00
description
Used to attach fatty acid residues and other derivatives at the lysine sidechain in GLP-1 analogues, like Liraglutide.
references
Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide; Ivan Guryanov, Alex Bondesan, Dario Visentini, Andrea Orlandin, Barbara Biondi, Claudio Toniolo, Fernando Formaggio, Antonio Ricci, Jacopo Zanon, Walter Cabri; J. Pep.Sc. 2016; 22(7): 471-479. DOI:10.1002/psc.2890.
WO 2003045418 A1; WO 2017138855 A1; WO 2015188197 A2; WO 2011066869 A1.
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