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N3-L-Glu(Dde)-OtBu
Chemical name: tert-butyl (S)-2-azido-5-(4,4-dimethyl-2,6-dioxocyclohexylidene)-5-hydroxypentanoate
- Product code:RL-8700
- Formula:C17H25N3O5
- Storage temperature:2-8°C
- Molecular weight:351.40 g/mol
- Purity :min. 98.0%
from €120.00
description
Building-block used to produce a novel cleavable linker developed by the laboratory of Prof. M. A. Brimble.
references
Use of a Cyclic á-Alkylidene-â-Diketone as a Cleavable Linker Strategy for Antibody-Drug Conjugates; J. T. W. Tong, M. Sarwar, M. Ahangarour, P. A. Hume, G. M. Williams, M. A. Brimble, I. Kavianinia; J. Am. Chem. Soc. 2024; 146(34): 23717-23728. https://doi.org/10.1021/jacs.4c04567
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