DMSO/EtOAc (2 : 8)

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Chemical name: Ethyl acetate/ Dimethyl sulfoxide 80/20 (v/v)

  • Product code:SOL-021
  • CAS No.:67-68-5 / 141-78-6
  • Formula:C2H6OS / C4H8O2
  • Molecular weight:78.13 / 88.11 g/mol

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references

Optimization of peptide synthesis time and sustainability using novel eco-friendly binary solvent systems with induction heating on an automated peptide synthesizer; L. Pacini, M. Muthyala, L. Aguiar, R. Zitterbart, P. Rovero, A. M. Papini; Journal of peptide science : an official publication of the European Peptide Society 2024; 30: e3605. https://doi.org/10.1002/psc.3605

Harnessing polarity and viscosity to identify green binary solvent mixtures as viable alternatives to DMF in solid-phase peptide synthesis; V. Martin, S. Jadhav, P. H. G. Egelund, R. Liffert, H. Johansson Castro, T. Krüger, K. F. Haselmann, S. Thordal Le Quement, F. Albericio, F. Dettner, C. Lechner, R. Schönleber, D. S. Pedersen; Green Chemistry 2021; 23: 3295-3311. https://doi.org/10.1039/d1gc00603g

Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides; L. Ferrazzano, D. Corbisiero, G. Martelli, A. Tolomelli, A. Viola, A. Ricci, W. Cabri; ACS Sustainable Chemistry & Engineering 2019; 7: 12867-12877. https://doi.org/10.1021/acssuschemeng.9b01766


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