Welcome to Iris Biotech
For better service please confirm your country and language we detected.
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemical name: N-alpha-benzyloxycarbonyl-L-phenylalanyl-L-arginine-7-amido-4-methylcoumarin hydrochlorid // Synonyms: Z-FR-AMC, Z-Phe-Arg-7-amido-4-methylcoumarin hydrochloride, N-CBZ-Phe-Arg-AMC,Z-Phe-Arg-AMC*HCl, Benzyl((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-1-ox o-3-phenylpropan-2-yl)carbamate; Component CAS 651
from €240.00
Z-Phe-Arg-AMC is a fluorogenic substrate for various serine proteases like cathepsins, kallikrein and plasmin. Substrate of papain, cruzain and trypsin. Absorption/emission of substrate = 330/390 nm (weak fluorescence). Absorption/emission of end product (AMC) = 342/441 nm (strong fluorescence).
Proteolytic Activity of Human Osteoclast Cathepsin K. Expression, Purification, Activation, and Substrate Identification; M. J. Bossard, T. A. Tomaszek, S. K. Thompson, B. Y. Amegadzie, C. R. Hanning, C. Jones, J. T. Kurdyla, D. E. McNulty, F. H. Drake, M. Gowen, and M. A. Levy; J. Biol. Chem. 1996; 12517. https://doi.org/10.1074/jbc.271.21.12517.
A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers; A. L. Niles, R. A. Moravec, P. E. Hesselberth, M. A. Scurria, W. J. Daily, T. L. Riss; Anal. Biochem. 2007; 366(2): 197-206. https://doi.org/10.1016/j.ab.2007.04.007.
Bottom-Up Construction of an Adaptive Enzymatic Reaction Network; B. Helwig, B. van Sluijs, A. A. Pogodaev, S. G. J. Postma, W. T. S. Huck; Angew. Chem. Int. Ed. 2018; 57: 14065. https://doi.org/10.1002/anie.201806944.
Please send me more information about