Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Linkerology
-
His-Tag for Specific Linker Attachment
Learn, how His-Tag can be used for specific linker attachment. Another example in our LINKEROLOGY series of sophisticated linker technologies.
Read more
-
Product of the Month: Dde-based Linkers
Placing Dde as one terminal group of a linker and a functional group prone for conjugation as the other or using Dde as the central connective portion of a linker, allows for the creation of new bifunctional linkers.
Read more
-
Subject Focus: Linkerology
The ever-growing sophistication and variation in linker design have given rise to a new and distinct field of knowledge in synthetic chemistry termed Linkerology. Discover our expertise and panoply of new cutting-edge tailor-made linker constructs for the latest state-of-the-art bioconjugations.
Read more
-
Cleavable Bifunctional Biotin-Linkers
Biotinylation of proteins and their purification via Streptavidin beads is a widely applied method.
Read more
-
The Safety-Catch Acid-Labile (SCAL)-Linker
The SCAL linker offers superior chemical stability and permits a variety of orthogonal solid-phase approaches. It is fully compatible with the Fmoc-, Boc- and Alloc- strategies. Cleavage can be performed either by a simultaneous, or by a two-step reduction/acidolysis procedure to afford peptide amides.
Read more
-
3rd Generation Click Chemistry: Tetrazine and TCO Derivatives for Copper-free Conjugation
The reaction between a tetrazine (Tz) and a trans-cyclooctene (TCO) is the innovative third generation Click reaction that proceeds without the use of copper or other catalyst. It is rapid, fully bioorthogonal and excels at very low concentrations.
Read more
-
Photo-Linker for Peptide Amides and Acids
Peptide linkers usually are cleaved under acidic conditions or using two-step procedures. Photocleavage proceeds under neutral conditions using UV light and can either be performed in batch or using flow chemistry.
Read more
-
Linkers for Antibody-Drug Conjugation (ADC)
Cleavable dipeptide linkers like Val-Ala and Val-Cit rely on processes inside the cell to liberate the payload, as they undergo rapid hydrolysis in the presence of lysosomal extracts or purified human cathepsin B.
Read more
-
New Click Linker
Click chemistry has developed to a widely used conjugation technique. Here are our latest developments of new short linker for hydrophilic and hydrophobic applications.
Read more -
Phthalimidooxy PEG-based cross linkers
Phthalimidooxy PEG-based cross linkers form stable oximes with aldehydes, also latent ones as present in carbohydrates. Their reactivity is sufficiently mild for a broad used in creating conjugates with sensitive biologics.
Read more
