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NHS-palmitic acid
Chemical name: N-(palmitoyloxy)-succinimide // Synonyms: 2,5-dioxopyrrolidin-1-yl palmitate, Palmitic acid N-hydroxysuccinimide ester, Hexadecanoic acid N-hydroxysuccinimide ester, N-Hydroxysuccinimide palmitate, Palmitic acid NHSester, Palmitic acid succ inimide ester, Succinimidyl hexadecanoate, Palm-NH
- Product code:RL-3810
- CAS No.:14464-31-4
- Formula:C20H35NO4
- Storage temperature:-20°C
- Molecular weight:353,50 g/mol
- Purity :min. 98%
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description
Fatty acids are key components and abundant constituents of all biological systems and are subject of many clinical, nutritional, and metabolic studies as they play a crucial role for normal functioning at all levels of an organism. Protein lipidation/fatty acylation, a common co- and post-translational modification of proteins plays important roles in human physiology. Palmitoylation represents one of the major post translational modifications responsible for protein activity control.
Keep dry and store at -20 °C.
references
Controls on Polymer Molecular Weight May Be Used To Control the Size of Palmitoyl Glycol Chitosan Polymeric Vesicles; W. Wang, A. M. McConaghy, L. Tetley, I. F. Uchegbu; Langmuir 2001; 17(3): 631-636. https://doi.org/10.1021/la001078w.
Incorporation of fatty acid into food protein: palmitoyl soybean glycinin; Z. Haque, T. Matoba, M. Kito; J. Agric. Food Chem. 1982; 30(3): 481-486. https://doi.org/10.1021/jf00111a018.
Palmitoyl derivatives of interferon alpha: Potential for cutaneous delivery; M. Foldvari, S. Attah-Poku, J. Hu, Q. Li, H. Hughes, A. Babiuk Lorne, S. Kruger; J. Pharm. Sci. 1998; 87(10): 1203-1208. https://doi.org/10.1021/js980146k.
Palmitate-derivatized antibodies can function as surrogate receptors for mediating specific cell-cell interactions; A. S. Colsky, J. S. Peacock; J. Immunol. Methods 1989; 124(2): 179-187. https://doi.org/10.1016/0022-1759(89)90351-7.
Synthesis of fatty acyl CoA and other thiol esters using N-hydroxysuccinimide esters of fatty acids; A. Al-Arif, M. Blecher; J. Lipid Res. 1969, 10(3): 344-345. https://doi.org/10.1016/S0022-2275(20)43095-0.
Water-soluble fatty acid derivatives as acylating agents for reversible lipidization of polypeptides; H. M. Ekrami, A. R. Kennedy; W.-C. Shen; FEBS Letters 1995; 371(3): 283-286. https://doi.org/10.1016/0014-5793(95)00910-2.
Synthesis of palmitoyl derivatives of insulin and their biological activities; M. Hashimoto, . Takada, Y. Kiso, S. Muranishi; Pharm. Research 1989; 6: 171-176. https://doi.org/10.1023/A:1015992828666.
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