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Fmoc-L-Lys(Boc)[13C6;15N2]-Trt TG R
Chemischer Name: Fmoc-L-Lys(Boc) (13C6, 99%; 15N2, 99%) TentaGel R TRT Resin
- Art-Nr.:RAI1217
- Lagertemperatur:2-8°C
- Partikelgröße:90 µm
- Beladung:0.1 - 0.2 mmol/g
Ab 1.410,00 €
description
TentaGel® resins consist of low cross-linked polystyrene on which poly(ethylene glycol) with a molecular weight of 3000 Da is grafted. The PEG spacer is attached to the polymer matrix via an ether bond, which shows high stability towards acid treatment and minimizes PEG leaching. The properties of TentaGel® resins are dominated by PEG, which solubilizes both hydrophobic and hydrophilic compounds, combined with high diffusion rates and excellent swelling in a wide range of solvents from e.g. toluene to water. TentaGel® resins are pressure stable and can be used in batch processes as well as under continuous flow conditions.
This resin can be used to synthesize peptides containing heavy labeled amino acids, making them ideal for MS analysis and quantification of complex peptide and protein mixtures.
references
Development of a multiplex mass spectrometry method for simultaneous quantification of urinary proteins related to respiratory health; S. J. D. Nauwelaerts, N. H. C. Roosens, A. Bernard, S. C. J. De Keersmaecker, K. De Cremer; Sci. Rep. 2021; 11: 10107. https://doi.org/10.1038/s41598-021-89068-9
Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking; J. R. Wiœniewski, C. Wegler, P. Artursson; J. Proteome Res. 2019; 18(1): 217-224. https://doi.org/10.1021/acs.jproteome.8b00549
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