Fmoc-L-Arg(Pbf)-MPPA

Chemischer Name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine-3-(4-oxymethylphenoxy)propionic acid // Synonyme: 3-(4-(((N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-omega-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-L-arginyl)oxy)methyl)phenoxy)propanoic acid,N-[(9H-Fluoren-9-ylmethoxy)carbonyl]- N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfon

  • Art-Nr.:LW00203
  • CAS Nr.:1202179-60-9
  • Lagertemperatur:2-8°C
  • Formel:C44H50N4O10S
  • Molare Masse:826,96 g/mol

Ab 150,00 €

Gruppiert Produkte - Artikel
Anzahl Verpackungsgröße Preis SKU Warenverfügbarkeit
1 g
150,00 €
LW00203.0001
<10 Arbeitstage
5 g
595,00 €
LW00203.0005
<10 Arbeitstage
description

This Fmoc-amino acid-MPPA linker serves as precursor for the linkage to e.g. aminomethyl supports by standard coupling procedures. By this method, a low (max 0.5%) and reproducible epimerization level of the C-terminal amino acid in your peptide is guaranteed.


references

Improved approach for anchoring Nalpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis; F. Albericio, G. Barany; Int. J. Peptide. Protein. Res. 1985; 26(1): 92-97. https://doi.org/10.1111/j.1399-3011.1985.tb03182.x.


Amino acid derivatives used as agents bonding to a solid support; NeoMPS S.A. 2005; French Patent Application FR 0402973, International Patent Application WO2005/095332.


Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines; P. W. R. Harris, M. A. Brimble; Pept. Sci. 2015; 104(2): 116-127. https://doi.org/10.1002/bip.22621.

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