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Continue to Iris Biotech GmbHSend request to US distributorChemischer Name: N-alpha-MaleimidoN-beta-t-butyloxycarbonyl-L-2,3-diaminopropionic acid pentafluorophenolate // Synonyme: Mal-Dap(Boc)-OPfp, Mal-Dpr(Boc)-OPfp, 2,3,4,5,6-pentafluorophenyl (2S)-3-{[(tert-butoxy)carbonyl]amino}-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
Ab 95,00 €
Mal-Dap(Boc)-OPfp is used in drug conjugate construction leading to more stable conjugates due to Dap neighboring-group assistance. This strategy is widely used in antibody-drug conjugation (ADC).
Lyon, Robert; Burke, Patrick; Hunter, Joshua; PCT Int. Appl. (2015), WO 2015057699 A2;
Cong, Qiang; Gangwar, Sanjeev; Rangan, Vangipuram S.; Sung, Mei-Chen; PCT Int. Appl. (2017), WO 2017196598 A1;
Burke, Patrick J.; Courter, Joel; PCT Int. Appl. (2017), WO 2017096311 A1.