Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Währung
EUR
Schneller Kontakt
Bitte senden Sie mir mehr Informationen über
Fmoc-D-Ser(Msbh)-OH
Chemischer Name: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(bis(4-(methylsulfinyl)phenyl)methyl)-D-serine // Synonyme: Safety-Catch D-Serine
- Art-Nr.:FAA8837
- Formel:C33H31NO7S2
- Lagertemperatur:2-8°C
- Molare Masse:617,73 g/mol
Ab auf Anfrage
description
MsbH is a safety-catch protecting group for cysteines, serines and threonines. It is stable to the conditions applied in both Boc and Fmoc chemistry. By reduction of the sulfoxides to thioethers with NH4I and dimethylsulfide in TFA, the MsbH protection becomes instable and is instantly removed.
references
The p-(methylsulfinyl)benzyl group: a trifluoroacetic acid (TFA)-stable carboxyl-protecting group readily convertible to a TFA-labile group; J. M. Samanen, E. Brandeis; J. Org. Chem. 1988; 53(3): 561-569. https://doi.org/10.1021/jo00238a016
Solid-Phase Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme; F. Albericio, S. Noki, E. Brasil, H. Zhang, T. Bruckdorfer, B. G. de la Torre; J. Org. Chem. 2022; 87: 9443-9453. https://doi.org/10.1021/acs.joc.2c01056
Benötigen Sie weitere Informationen über dieses Produkt?
kontaktieren Sie uns
Produkte, die Sie auch interessieren könnten!
