Boc-L-His(2-Oxo)-OH

Nom chimique: Boc-2-oxohistidine // Synonymes: (S)-2-((tert-butoxycarbonyl)amino)-3-(2-oxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acid, Boc-2-Oxo-Histidine, Boc-Oxohistidine, Boc-2-Oxo-L-Histidine, Boc-2-Oxohistidine,Boc-His(2-Oxo)-OH

  • n° Art.:BAA4850
  • n° CAS:2580114-21-0
  • Formule:C11H17N3O5
  • Storage temperature:-20°C
  • Masse moléculaire:271,27 g/mol

from 800,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
100 mg
800,00 €
BAA4850.0100
<10 jour ouvrables
250 mg
1 600,00 €
BAA4850.0250
<10 jour ouvrables
description

Histidine is one of the major oxidation targets due to its metal‐chelating property and susceptibility to metal‐catalyzed oxidation. The major product of histidine oxidation, 2-oxohistidine, has been identified as a stable marker of oxidative damage in biological system, associated with aging and neurodegenerative disorders. Peptide probes and peptide antigens containing 2‐oxohistidine will help to advance the study of non‐enzymatic posttranslational modification.


references

Synthesis of peptides containing 2‐oxohistidine residues and their characterization by liquid chromatography‐tandem mass spectrometry; C.‐F. Huang, Y.‐H. Liu, H.‐C. Tai; J. Pept. Sci. 2015; 21: 114-119. https://doi.org/10.1002/psc.2735

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