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Search results for: 'cysteine'
PotM: Furan-Crosslinking and 5HP2O as Maleimide Alternative
Game Changer for Protein Modification: Discover oxidation-induced furan...
Read more...A Fluorescent Probe for “Hard and Soft” Reactive Metabolites
Discover CysGluDan, a new fluorescent probe for the detection of reactive...
Read more...Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and...
Read more...Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and...
Read more...GGFG Motif for ADC Construction
To address both chemical and IP considerations in self-immolating linker...
Read more...Bioisosteric Argininine Analogs
Same but different! Expand your possibilities for peptide modification and...
Read more...Protecting Groups in SPPS
Mix & Match. Discover typically employed protecting groups used to...
Read more...“Power On” – Activity Control by Photocaging
Discover photocages – photosensitive protecting groups that are removed by...
Read more...2-Cyanopyridines for Click-Like Reactions
Have an additional ace up your sleeve for selective and efficient peptide...
Read more...Aminothiols for Versatile Side-Chain Modification
Beyond cysteines: Unlock targeted side-chain modifications of your peptides...
Read more...PotM: Oligomeric Sarcosine Building Blocks
You are looking for monodisperse Sarcosines? You want to use Sarcosine for...
Read more...Process Development – From Discovery to Scale-up
Ongoing research efforts lead to the discovery of innovative building blocks...
Read more...Selective Lysine Labeling with Squaric Acid
Keeping control! PEGylating reagents with a squaric acid ethyl ester react...
Read more...PotM: TCEP as Versatile Reducing Agent
TCEP is an effective reductant for disulfide bonds and a versatile reagent...
Read more...Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation
Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so...
Read more...Carbamidomethylated Cysteine as SPPS Building Block
Our building block Fmoc-L-Cys(Cam)-OH enables peptides resembling reduced and...
Read more...Maleimide Crosslinkers
Maleimides provide versatile options for connecting payloads to proteins and...
Read more...PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation
Herein, we present functionalized perfluorobiphenyl building blocks which can...
Read more...Amino-PEG-Acids
PEGs are being used as spacers, as hydrophilic decoration, and building...
Read more...Acylation Efficiencies on Ser and Thr Pseudoproline Monomers
In two joint studies together with Prof. F. Albericio we investigated the...
Read more...Review – Product Highlights 2022
Curious about our latest portfolio additions from July to December 2022 and...
Read more...Abraligabra - Reagents and Building Blocks for Chemical Ligation
We can’t get enough of new products and innovations! Read this blog to get...
Read more...PotM: His Tags for the Chemical Modification of Peptides
Jensen et al. developed two methods that use poly-His sequences to direct the...
Read more...PotM: Fmoc-Ser(Msbh)-OH
You are working on complex peptides and are looking for a new level of...
Read more...Process Development of SPPS
From mg synthesis of a peptide up to bulk quantities often makes a huge...
Read more...A Systematic Comparison of Different Methods to Tackle Aspartimide Formation
Read on for detailed information on the results of our comparative study on...
Read more...Solid-Phase Synthesis of an “Inaccessible” hGH-Derived Peptide Using a Pseudoproline Monomer and SIT-Protection for Cysteine
Herein, we report the first-time SPPS of a special peptide sequence via...
Read more...Resins for Solid Phase Peptide Synthesis (Part 2)
You want to get an overview about the various resins available at Iris...
Read more...PotM: Substrates for Fusion (Halo/Snap/Clip)-Tagged Proteins
Discover our selection of substrates for Halo-, Snap-, and Clip-tagged...
Read more...Review – Product Highlights 2021
Herein, we summarize certain product highlights and innovations, which we...
Read more...Workshop Advances on Cysteine Protecting Groups
You missed our workshop featuring Prof. Dr. Fernando Albericio (University of...
Read more...Pseudoproline Monomers
Typically known and employed as preformed dipeptides, we are presenting...
Read more...Refill your Chemical Stocks
Back in the lab after enjoying your holidays? Motivated to run new...
Read more...Hydrazone Resins as Alternative to SEA Resins
Discover the versatile applications of hydrazone resins e.g. for the...
Read more...PotM: Seleno Amino Acids
Selenocysteine (Sec) plays a crucial role for various biological processes,...
Read more...PotM: Functionalized Biotinylation Reagents
Iris Biotech offers a variety of (functionalized) biotin and desthiobiotin...
Read more...About the Advantages of Pseudoproline Dipeptides
Serine- and Threonine-derived oxazolidines as well as Cysteine-derived...
Read more...Thiol- and Amine Reactive Crosslinkers
Iris Biotech offers hetero-bifunctional crosslinkers bearing an...
Read more...Fmoc-L-Cys(Palm)-OH – A S-palmitoylated Cysteine building block
Interested in studying the effect of palmitoylation on your peptide’s...
Read more...Facilitating the synthesis of hydrophobic peptides and proteins
Cys(Aapam): an Alloc protected Phacm linker as removable side chain...
Read more...DACNs for Strain-Promoted Azide-Alkyne Cycloadditions (SPAAC)
Herein we present substituted diazacyclononynes (DACNs) as versatile tools...
Read more...Arginine Derivatives Suitable for Side-Chain Derivatization
Herein we present two arginine derivatives, in which the native guanidino...
Read more...PotM: SIT – A New Cysteine Protecting Group
The new disulfide-based protecting group sec-isoamyl mercaptan (SIT) is fully...
Read more...Modifications of Methionine
Methionine is particularly prone to oxidation by atmospheric oxygen in vitro...
Read more...Thiol-reactive Linkers for ADCs
The thiosuccinimide linkage is a prominent connective motif resulting from...
Read more...Fighting SARS-CoV-2
Fighting COVID-19 by modifying essential viral proteins via glycation through...
Read more...Nitrodibenzofuran (NDBF) based Photocleavable Protecting Groups
Nitrodibenzofuran (NDBF) is a photocleavable side chain protecting group that...
Read more...Alkyne Amino Acids for Click Chemistry and other Conjugations:
Alkyne amino acids allow for Click conjugations and other types of chemistry....
Read more...L-Cysteine from non-human/non-animal origin
Iris Biotech offers L-Cysteine Hydrochloride Monohydrate from Cystine, which...
Read more...Phenyl-, Cyclohexyl- and BCP-Amino Acids
Sidechain-derivatized amino acids have shown great potential in enhancing...
Read more...Product of the Month: Fmoc-L-Cys(Allocam)-OH for 1-Step On-Resin Disulfide Bond Formation
The Allocam protecting group allows for selective deprotection and disulfide...
Read more...Protease Inhibitors
Protease inhibitors are molecules that inhibit protease function by binding...
Read more...Fmoc-L-Cys(Propargyl)-OH
This alkyne-functionalized cysteine building block can be incorporated into...
Read more...Fmoc Deprotection Reagents
The Fmoc group is the most frequently used protecting group in peptide...
Read more...Standard Fmoc Amino Acid Building Blocks
Amino acids of high quality are crucial for the synthesis of peptides with a...
Read more...Photocleavable NCL-Auxiliary Glycine
This innovative auxiliary facilitates Native Chemical Ligation at the...
Read more...Omniligase-1 for Efficient Peptide Ligation
Omniligase-1 enables efficient and racemization-free ligation of two...
Read more...The Safety-Catch Acid-Labile (SCAL)-Linker
The SCAL linker offers superior chemical stability and permits a variety of...
Read more...Msbh, a Safety Catch Cysteine Protecting Group for the Synthesis of Cyclic Peptides
The regioselective formation of multiple disulfide bonds is often a synthetic...
Read more...New: Cysteine-Pseudoproline
Pseudoprolines derived from Serine and Threonine have developed to standard...
Read more...Linkers for Antibody-Drug Conjugation (ADC)
Cleavable dipeptide linkers like Val-Ala and Val-Cit rely on processes inside...
Read more...Photocleavable Cys Protecting Group
This oNv (2-Nitroveratryl) is the latest addition to our repertoire of...
Read more...Benzotriazole Amino Acids
Benzotriazol activated carboxylic acids: Fast reaction (within minutes) at...
Read more...Thio-Prolines - Rigid Homo-Cys Analogues
Cysteins and homocysteins are found in many natural and artificial peptide...
Read more...Product of the Month: Fmoc-L-Cys(Dpm)-OH
Any amino acid can be functionalized on the N-terminus with oxalic acid and...
Read more...DTT (Cleland's Reagent)
Cleland's reagent, also known as dithiothreitol or DTT is a water soluble...
Read more...Green Advantages of using Phacm for Cystein Protection
PGA (Penicillin G Amidase, Penicillin Acylase, Penicillin Amidohydrolase from...
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