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Fmoc-L-Pro(4,4-F2)-OH
Nom chimique: (S)-1-(9-Fluorenylmethyloxycarbonyl)-4,4-difluoro-pyrrolidine-2-carboxylic acid // Synonymes: (S)-Fmoc-4,4-difluoro-pyrrolidine-2-carboxylic acid, Fmoc-4,4-difluoro-proline, Fmoc-Pro(4,4,-F2)-OH
- n° Art.:FAA4290
- n° CAS:203866-21-1
- Formule:C20H17F2NO4
- Storage temperature:2-8°C
- Masse moléculaire:373,36 g/mol
from 150,00 €
references
MK-8325: A silyl proline-containing NS5A inhibitor with pan-genotype activity for treatment of HCV; A. G. Nair, Q. Zeng, O. Selyutin, S. B. Rosenblum, Y. Jiang, D. Y. Yang, K. Keertikar, G. Zhou, M. Dwyer, S. H. Kim, B. Shankar, W. Yu, L. Tong, L. Chen, R. Mazzola, J. Caldwell, H. Tang, S. Agrawal, R. Liu, R. Kong, P. Ingravallo, E. Xia, Y. Zhai, A. Nomeir, E. Asante-Appiah and J. A. Kozlowski; Bioorg Med Chem Lett 2018; 28: 1954-1957. https://doi.org/10.1016/j.bmcl.2018.03.049
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer; V. J. Somovilla, I. A. Bermejo, I. S. Albuquerque, N. Martinez-Saez, J. Castro-Lopez, F. Garcia-Martin, I. Companon, H. Hinou, S. I. Nishimura, J. Jimenez-Barbero, J. L. Asensio, A. Avenoza, J. H. Busto, R. Hurtado-Guerrero, J. M. Peregrina, G. J. L. Bernardes and F. Corzana; J Am Chem Soc 2017; 139: 18255-18261. https://doi.org/10.1021/jacs.7b09447
Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs; A. Adamska, A. Kluczyk, M. C. Cerlesi, G. Calo, A. Janecka and A. Borics; Bioorg Med Chem 2016; 24: 1582-8. https://doi.org/10.1016/j.bmc.2016.02.034
Synthesis and Pharmacological Evaluation of alpha4beta2 Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus; L. Tamborini, A. Pinto, R. Ettari, C. Gotti, F. Fasoli, P. Conti and C. De Micheli; ChemMedChem 2015; 10: 1071-8. https://doi.org/10.1002/cmdc.201500073
Both the cis-trans equilibrium and isomerization dynamics of a single proline amide modulate beta2-microglobulin amyloid assembly; V. Y. Torbeev and D. Hilvert; Proc Natl Acad Sci U S A 2013; 110: 20051-6. https://doi.org/10.1073/pnas.1310414110
Origin of the stability conferred upon collagen by fluorination; M. D. Shoulders, K. J. Kamer and R. T. Raines; Bioorg Med Chem Lett 2009; 19: 3859-62. https://doi.org/10.1016/j.bmcl.2009.03.168
Proline editing: a divergent strategy for the synthesis of conformationally diverse peptides; K. M. Thomas, D. Naduthambi, G. Tririya and N. J. Zondlo; Org Lett 2005; 7: 2397-400. https://doi.org/10.1021/ol0506720
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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