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Fmoc-L-Pro(4-CF3)-OH (2S,4S)
Nom chimique: (2S,4S)-1-(9-Fluorenylmethyloxycarbonyl)-4-trifluoromethyl-pyrrolidine-2-carboxylic acid // Synonymes: (2S,4S)-Fmoc-4-trifluoromethyl-pyrrolidine-2-carboxylic acid, Fmoc-4-trifluoromethyl-proline (2S,4S), Fmoc-Pro(4-CF3)-OH (2S,4S)
- n° Art.:FAA4320
- n° CAS:1242934-32-2
- Formule:C21H18F3NO4
- Storage temperature:2-8°C
- Masse moléculaire:405,37 g/mol
from 225,00 €
references
The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L; E. Buommino, A. Carotenuto, I. Antignano, R. Bellavita, B. Casciaro, M. R. Loffredo, F. Merlino, E. Novellino, M. L. Mangoni, F. P. Nocera, D. Brancaccio, P. Punzi, D. Roversi, R. Ingenito, E. Bianchi and P. Grieco; ChemMedChem 2019; 14: 1283-1290. DOI: https://doi.org/10.1002/cmdc.201900221.
Comparative effects of trifluoromethyl- and methyl-group substitutions in proline; V. Kubyshkin, S. Pridma and N. Budisa; New Journal of Chemistry 2018; 42: 13461-13470. DOI: https://doi.org/10.1039/c8nj02631a.
Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode; E. A. Jurica, X. Wu, K. N. Williams, A. S. Hernandez, D. S. Nirschl, R. A. Rampulla, A. Mathur, M. Zhou, G. Cao, C. Xie, B. Jacob, H. Cai, T. Wang, B. J. Murphy, H. Liu, C. Xu, L. K. Kunselman, M. B. Hicks, Q. Sun, D. M. Schnur, D. F. Sitkoff, E. A. Dierks, A. Apedo, D. B. Moore, K. A. Foster, M. E. Cvijic, R. Panemangalore, N. A. Flynn, B. D. Maxwell, Y. Hong, Y. Tian, J. J. Wilkes, B. A. Zinker, J. M. Whaley, J. C. Barrish, J. A. Robl, W. R. Ewing and B. A. Ellsworth; Journal of medicinal chemistry 2017; 60: 1417-1431. DOI: https://doi.org/10.1021/acs.jmedchem.6b01559.
gamma-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state (19)F-NMR peptide studies; V. Kubyshkin, S. Afonin, S. Kara, N. Budisa, P. K. Mykhailiuk and A. S. Ulrich; Org Biomol Chem 2015; 13: 3171-3181. DOI: https://doi.org/10.1039/c5ob00034c.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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