Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
Fmoc-L-Dap(Ns)-OH
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-nosyl-L-2,3-diaminopropionic acid // Synonymes: Fmoc-Dapa(Ns)-OH, Fmoc-Dpr(Ns)-OH, Fmoc-Dap(Ns), Fmoc-Dap(Ns)-OH, Fmoc-Dap(Nosyl), (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-nitrobenzenesulfonamido)propanoic acid,N-alpha-Fmoc-N-beta- Ns-L-2,3-diaminopropionic acid
- n° Art.:FAA7310
- n° CAS:867213-27-2
- Formule:C24H21N3O8S
- Storage temperature:2-8°C
- Masse moléculaire:511,50 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 80,00 €
description
Used as an orthogonally protected Dap building-block in SPPS. The Nosyl-group can be utilized to enable Mitsunobu-reaction or N-alkylations at the side-chain N atom.
references
Solid-Phase Synthesis of Amine-Bridged Cyclic Enkephalin Analogues via On-Resin Cyclization Utilizing the Fukuyama−Mitsunobu Reaction; Yosup Rew, Murray Goodman; J. Org. Chem. 2002; 67(25): 8820-8826. DOI: 10.1021/jo020447l.
Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves. Monfregola L., De Luca S.; Amino Acids 2011; 41(4): 981-990. DOI: 10.1007/s00726-010-0798-6.
New synthetic strategy for o-NBS protected amino acids and their use in synthesis of mono-benzylated peptides; Stefano de Luca, Raffaella Della Moglie, Antonia De Capua, Giancarlo Morelli;
Tetrahedron Lett. 2005; 46(39): 6637-6640. DOI: 10.1016/j.tetlet.2005.07.154.
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Des produits qui pourraient également vous intéresser!
