Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
Fmoc-3-amino-3-(adamantan-1-yl)-propionic acid
Nom chimique: 3-(9-Fluorenylmethyloxycarbonyl)-amino-3-(adamantan-1-yl)-propionic acid // Synonymes: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((3r,5r,7r)-adamantan-1-yl)propanoic acid, (R,S)-Fmoc-3-amino-3-(adamantan-1-yl)-propionic acid
- n° Art.:FAA8520
- n° CAS:2094377-05-4
- Formule:C28H31NO4
- Storage temperature:2-8°C
- Masse moléculaire:445,56 g/mol
from Sur demande
description
The highly lipophilic, symmetrical adamantly motif is reported for its hydrophobic bulk and spherical shape, proposed by modelling to favor hydrophobic contacts in protein binding pockets. Thus, this adamantane building block can be used for structure-activity-relationship studies. Furthermore, adamantane is part of various medicinally important compounds.
references
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D; A. Vulpetti, N. Ostermann, S. Randl. T. Yoon, A. M. Sweeney, F. Cumin, E. Lorthiois, S. Rüdisser, P. Erbel, J. Maibaum; ACS Med. Chem. Lett. 2018; 9(5): 490-495. https://doi.org/10.1021/acsmedchemlett.8b00104.
Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists; O. Karoutzou, S.-H. Kwak, S.-D. Lee, D. Martínez-Falguera, F. X. Sureda, S. Vázquez, Y.-C. Kim, M. Barniol-Xicota; Molecules 2018; 23(1): 230. https://doi.org/10.3390/molecules23010230.
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Des produits qui pourraient également vous intéresser!
