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Fmoc-4-AMCHC-OH
Nom chimique: trans-4-(9-Fluorenylmethyloxycarbonylaminomethyl)-cyclohexanoic acid // Synonymes: Fmoc-tranexamic acid, trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid, Fmoc-4-Amc-OH, Fmoc-Trx-OH
- n° Art.:FAA1647
- n° CAS:167690-53-1
- Formule:C23H25NO4
- Storage temperature:2-8°C
- Masse moléculaire:379,46 g/mol
- Pureté:min. 99%
from 55,00 €
description
Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody-Drug Conjugates (Kadcyla®, IMMU-132).
references
Benesova, Martina; Bauder-Wuest, Ulrike; Schaefer, Martin; Klika, Karel D.; Mier, Walter; Haberkorn, Uwe; Kopka, Klaus; Eder, Matthias; J. Med. Chem. 2016; 59(5): 1761-1775. DOI:10.1021/acs.jmedchem.5b01210;
Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1.
Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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