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Fmoc-L-Sec(Mob)-OPfp
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-4-methoxybenzyl selenocysteine pentafluorophenyl ester // Synonymes: Fmoc-L-Sec(pMeOBzl)-OPfp, Fmoc-Sec(MBzl)-OPfp, Fmoc-L-Sec(Pmb)-OPfp, Fmoc-Sec(Mob)-OPfp, Fmoc-L-4-methoxybenzyl selenocysteine pentafluorophenyl ester, 2,3,4,5,6-pentafluorophenyl(2R)-2-({[(9H-fluor en-9-yl)methoxy]carbonyl}amino)-3-{[(4-methoxyphen
- n° Art.:FAA8760
- n° CAS:939431-43-3
- Formule:C32H24F5NO5Se
- Storage temperature:-20°C
- Masse moléculaire:676,51 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 162,00 €
description
Isomeric purity >99.9%. Building block for the introduction of selenocysteine by SPPS. Peptides containing selenocysteine can be cleaved from the resin with simultaneous side-chain deprotection by treatment with 5% (v/v) water, 95% (v/v) trifluoroacetic acid (TFA), 0.4 M 2,2’-dithiobis(5-nitropyridine) (DTNP) for 7 min at 60 °C or 2 h at RT.
references
References:
Selenocysteine-Mediated Native Chemical Ligation; R. Quaderer, A. Sewing, D. Hilvert; Helv. Chim. Acta 2001; 84(5): 1197-1206; https://doi.org/10.1002/1522-2675(20010516)84:5<1197::AID-HLCA1197>3.0.CO;2-%23
Selenoglutathione: Efficient Oxidative Protein Folding by a Diselenide; J. Beld, K. J. Woycechowsky, D. Hilvert; Biochemistry 2007; 46(18): 5382-5390. https://doi.org/10.1021/bi700124p.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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