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N3-L-Lys(Mtt)-OH
Nom chimique: (S)-2-Azido-6-[(4-methyltrityl)amino]hexanoic acid // Synonymes: N3-Lys(Mtt)-OH, alpha-Azido-N-epsilon-p-metyltrityl-L-lysine
- n° Art.:HAA2880
- n° CAS:1333231-26-7
- Formule:C26H28N4O2
- Storage temperature:2-8°C
- Masse moléculaire:428,53 g/mol
- Pureté:min. 99%
- Pureté Énantiomérique:min. 99,7%
from 108,00 €
description
Amino acid building block for introducing azido functions into peptide sequences at the N-terminal position. The azido moiety can be employed in standard click conjugation or serve as masked amino function, which it can be transferred into by reduction with phosphines.
references
alpha,beta-Diamino Acids: Biological Significance and Synthetic Approaches; Alma Viso, Roberto Fernández de la Pradilla, Ana García, and Aida Flores; Chemical Reviews 2005; 105(8): 3167-3196. DOI: 10.1021/cr0406561.
Update 1 of: alpha,beta-Diamino Acids: Biological Significance and Synthetic Approaches; Alma Viso, Roberto Fernández de la Pradilla, Mariola Tortosa, Ana García, and Aida Flores; Chem. Rev. 2011; 111: PR1-PR42. DOI 10.1021/cr100127y.
Orthogonally Protected Cyclo-ß-tertapeptides as Solid-Supported Scaffolds for the Synthesis of Glycoclusters; Pasi Virta, Marika Karskela, Harri Lönnberg; J.Org.Chem 2006; 71: 1989-1999.
Stereocontrolled Route to Vicinal Diamines by [3.3] Sigmatropic Rearrangement of Allyl Cyanate: Asymmetric Synthesis of anti-(2R,3R)-and syn-(2R,3S)-2,3-Diaminobutanoic Acids; Yoshiyasu Ichikawa, Haruka Egawa, Takashi Ito, Minoru Isobe, Keiji Nakano, and Hiyoshizo Kotsuki; Org.Lett. 2006; 8(25): 5737-5740.
Efficient Synthesis of orthogonally protected ant-2,3-diamino acids; Stefania Capone, Annalisa Guaregna, Giovanni Palumbo, Silvana Pedatella; Tetrahedron 2005; 61: 6575-6579.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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