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H-L-Aha-OH
Nom chimique: 4-Azido-L-homoalanine // Synonymes: AHA, L-2-amino-4-azidobutanoic acid, L-azidohomoalanine, homoAZAL, Azhal, H-Dab(N3)-OH, H-gamma-azido-Abu-OH, L-gamma-azidohomoalanine, (S)-2-Amino-4-azidobutanoic acid,4-azido-homoalanine
- n° Art.:HAA9280
- n° CAS:120042-14-0
- Formule:C4H8N4O2
- Storage temperature:2-8°C
- Masse moléculaire:144,13 g/mol
- Pureté:min. 99%
- Pureté Énantiomérique:min. 99,9%
from 126,00 €
description
H-Dab(N3)-OH is incorporated into proteins that can be further selectively modified using Staudinger ligation or Click-chemistry.
Corresponding HCl salt: HAA5730.
references
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation; K. L. Kiick, E. Saxon, D. A. Tirrell, C. R. Bertozzi; PNAS 2002; 99(1): 19-24. https://doi.org/10.1073/pnas.012583299.
Cell Surface Labeling of Escherichia coli via Copper(I)-Catalyzed [3+2] Cycloaddition; A. J. Link, D. A. Tirrell; J. Am. Chem. Soc. 2003; 125(37): 11164-11165. https://doi.org/10.1021/ja036765z.
Presentation and Detection of Azide Functionality in Bacterial Cell Surface Proteins; A. J. Link, M. K. S. Vink, D. A. Tirrell; J. Am.
Chem. Soc. 2004; 126(34): 10598-10602. https://doi.org/10.1021/ja047629c.
Azidohomoalanine: A Conformationally Sensitive IR Probe of Protein Folding, Protein Structure, and Electrostatics; H. Taskent-Sezgin, J. Chung, P. S. Banerjee, S. Nagarajan, R. B. Dyer, I. Carrico, D. P. Raleigh; Angew. Chem. Int. Ed. 2010; 49(41): 7473-7475. https://doi.org/10.1002/anie.201003325.
Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry; C. Wu, Y. Jin, T. Schneider, D. R. Burnham, P. B. Smith, D. T. Chiu; Angew. Chem. Int. Ed. 2010; 49(49): 9436-9440. https://doi.org/10.1002/anie.201004260
Expanding the diversity of chemical protein modification allows post-translational mimicry; S. I. van Kasteren, H. B. Kramer, H. H. Jensen, S. J. Campbell, J. Kirkpatrick, N. J. Oldham, D. C. Anthony, B. G. Davis; Nature 2007; 446: 1105-109. https://doi.org/10.1038/nature05757.
Expanding One-Pot Cell-Free Protein Synthesis and Immobilization for On-Demand Manufacturing of Biomaterials; A. I. Benítez-Mateos, I. Llarena, A. Sánchez-Iglesias, F. López-Gallego; ACS Synth. Biol. 2018; 7(3): 875-884. https://doi.org/10.1021/acssynbio.7b00383.
SPAAC Pulse-Chase: A Novel Click Chemistry-Based Method to Determine the Half-Life of Cellular Proteins; T. M. Morey, M. Ali Esmaeili, M. L. Duennwald, R. J. Rylett; Front. Cell Dev. Biol. 2021; https://doi.org/10.3389/fcell.2021.722560.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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