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N3Ac-OPhOMe
Nom chimique: 4-Methoxyphenyl 2-azidoacetate
- n° Art.:RL-3010
- n° CAS:2546513-31-7
- Formule:C9H9N3O3
- Storage temperature:-20°C
- Masse moléculaire:207,19 g/mol
from 225,00 €
description
Methodology for highly selective N-terminal chemical acylation of expressed proteins. This 4-methoxyphenyl ester adds selectively to Gly-His-tags of proteins, while it does not react with epsilon amino functions of surface accessible lysines. Therefore, it expresses a unique possibility to label proteins regiospecific at the Gly-His tag position, enabling a wide application field in chemical biology and for biopharmaceuticals.
references
Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence; Manuel C. Martos-Maldonado, Christian T. Hjuler, Kasper K. Sørensen, Mikkel B. Thygesen, Jakob E. Rasmussen, Klaus Villadsen, Søren R. Midtgaard, Stefan Kol, Sanne Schoffelen, and Knud J. Jensen; Nature Communications 2018; 9: 3307. DOI: 10.1038/s41467-018-05695-3
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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