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Boc-D-Lys(Z)-OH
Chemical name: N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-D-lysine
- Product code:BAA1358
- CAS No.:55878-47-2
- Formula:C19H28N2O6
- Storage temperature:2-8°C
- Molecular weight:380.44 g/mol
from €190.00
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. BennyGerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.
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