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Boc-L-Lys(TFA)-OH
Chemical name: N-alpha-t-Butyloxycarbonyl-N-epsilon-trifluoracetyl-L-lysine // Synonyms: Boc-Lys(TFA)-OH
- Product code:BAA5790
- CAS No.:16965-06-3
- Formula:C13H21F3N2O5
- Storage temperature:2-8°C
- Molecular weight:342.31 g/mol
from €150.00
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy,
Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. BennyGerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014;
53: 9450-9455. DOI: 10.1002/anie.201402789.
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