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Product Focus
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HMPO: A pH-Responsive Linker for Targeted Drug Delivery
HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive, 1,6-self-immolative crosslinker derived from the natural product gallic acid. Discover its properties!
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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GGFG Motif for ADC Construction
To address both chemical and IP considerations in self-immolating linker applications, we propose shifting from the commonly used Val-Cit-PAB linker to the less explored Gly-Gly-Phe-Gly-formyl motif.
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Bioisosteric Argininine Analogs
Same but different! Expand your possibilities for peptide modification and fine-tuning by implementing Nω-carbamoylated arginine building blocks as bioisosteric arginine analogs.
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Bifunctional TentaGel® Resins
Encode beads with unique tags for combinatorial syntheses & screening. Build libraries & identify hits. Discover properties and applications of our novel bifunctional TentaGel® resins.
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Boc versus Fmoc for Solid Phase Peptide Synthesis
Wondering about the difference between Boc and Fmoc chemistry in solid phase peptide synthesis? Don't worry: in this short overview we will guide you through the basics of both strategies.
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Norbornenes – Will You Click Me?
Proposing norbornenes – strained, bicyclic alkenes for fast, copper-free, biocompatible click-conjugation with tetrazines. Read on for more details on applications and available products!
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Carboxymethyl Amino Acid Derivatives
Level up! Carboxymethyl-modified amino acid building blocks suitable for incorporation by solid-phase peptide synthesis. Learn more about available derivatives and their properties.
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“Power On” – Activity Control by Photocaging
Discover photocages – photosensitive protecting groups that are removed by irradiation with light of a defined wavelength, thus restoring the original, “active” state.
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2-Cyanopyridines for Click-Like Reactions
Have an additional ace up your sleeve for selective and efficient peptide modification, cyclization, and/or bioconjugation. Explore 2-cyanopyridines for click-like reactions. Get more information!
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