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Fmoc-Asp(Wang Resin)-OPP
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid-beta-(Wang-Resin)-alpha-2-phenylisopropyl ester // Synonyms: Fmoc-Asp(Alko Resin)-Opis, (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-((2-phenylpropan-2-yl)oxy)butanoic acid p-methoxybenzyl alcohol resin
- Product code:CAA1010
- Storage temperature:2-8°C
- Particle size :100-200 mesh
from €890.00
description
An Aspartic acid building block immobilized on Wang resins on its side chain for the synthesis of cyclic peptides on resinmodification. The 2-phenylisopropyl protecting group can be deprotected with 1% TFA in dichloromethane. PP protected amino acids are also less prone towards aspartamide formation.
references
C.Yue et al.; Tetrahedron Lett. 1993; 34: 323.
F.Dick et al.; Peptides 1996; Proceedings of the 24th European Peptide Symposium Edinborough, Scotland, p.339.
R.Ramage, R.Epton, eds. Mayflower Scientific Ltd., England (1998)
M.Mergler et al.; J.Pept.Sci. 2003; 9: 36.
S.M.Ocampo et al.; Org.Lett. 2005; 7: 4349.
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