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Fmoc-L-Lys(Trt)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trityl-L-lysine // Synonyms: Fmoc-Lys(Trt)-OH
- Product code:FAA1140
- CAS No.:111061-54-2
- Storage temperature:2-8°C
- Formula:C40H38N2O4
- Molecular weight:610.78 g/mol
from €60.00
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.
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