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Fmoc-L-Lys(N3)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-epsilon-azido-L-lysine // Synonyms: N-alpha-(9-Fluorenylmethyloxycarbonyl)-epsilon-azido-L-norleucine, (S)-6-azido-2-(Fmoc-amino)hexanoic acid, (S)-2-(9-Fluorenylmethyloxycarbonylamino)-6-azidohexanoic acid,Fmoc-6-azido-L-norleucine, Fmoc-L-azidolysine, Fmoc-L-Lys(N2), Fmoc-L-Lys(N3)
- Product code:FAA1793
- CAS No.:159610-89-6
- Formula:C21H22N4O4
- Storage temperature:2-8°C
- Molecular weight:394.42 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,9%
from €72.00
description
Fmoc-Lys(N3) is incorporated into peptides that can be further selectively modified using Staudinger ligation or Click-chemistry.
references
Weerapana, Eranthie; Wang, Chu; Simon, Gabriel M.; Richter, Florian; Khare, Sagar; Dillon, Myles B. D.; Bachovchin, Daniel A.; Mowen, Kerri; Baker, David; Cravatt, Benjamin F. Nature (London, United Kingdom) (2010), 468(7325), 790-795. DOI:10.1038/nature09472;
Cantel, Sonia; Le Chevalier Isaad, Alexandra; Scrima, Mario; Levy, Jay J.; DiMarchi, Richard D.; Rovero, Paolo; Halperin, Jose A.; D'Ursi, Anna Maria; Papini, Anna Maria; Chorev, Michael Journal of Organic Chemistry (2008), 73(15), 5663-5674. DOI:10.1021/jo800142s;
Cai, Hui; Zhang, Roushu; Orwenyo, Jared; Giddens, John; Yang, Qiang; LaBranche, Celia C.; Montefiori, David C.;Wang, Lai-Xi ACS Central Science (2018), 4(5), 582-589. DOI:10.1021/acscentsci.8b00060;
Reuther, James F.; Dees, Justine L.; Kolesnichenko, Igor V.; Hernandez, Erik T.; Ukraintsev, Dmitri V.; Guduru, Rusheel; Whiteley, Marvin; Anslyn, Eric V. Nature Chemistry (2018), 10(1), 45-50. DOI:10.1038/nchem.2847.
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