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Fmoc-beta,beta-diMe-Tyr(tBu)-OH (rac)
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-beta,beta-dimethyl-O-t-butyl-tyrosine (rac.) // Synonyms: (R,S)-Fmoc-beta,beta-dimethyl-O-t-butyl-tyrosine, 2-(Fmoc-amino)-3-(4-t-butoxyphenyl)-3-methylbutanoic acid,2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-tert-butoxyphenyl)-3-methylbutanoic acid
- Product code:FAA2660
- CAS No.:2446027-07-0
- Formula:C30H33NO5
- Storage temperature:2-8°C
- Molecular weight:487.59 g/mol
from €225.00
description
beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases.
references
Synthesis and Antimitotic/Cytotoxic Activity of Hemiasterlin Analogues; James A. Nieman, John E. Coleman, Debra J. Wallace, Edward Piers,Lynette Y. Lim, Michel Roberge, and Raymond J. Andersen; J. Nat. Prod. 2003; 66: 183-199. DOI: 10.1021/np020375t.
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