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Fmoc-N(oNv)-Gly-OH
Chemical name: N-alpha (9-Fluorenylmethyloxycarbonyl)-N-alpha-(o-nitroveratryl)-glycine // Synonyms: 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(4,5-dimethoxy-2-nitrobenzyl)amino)acetic acid, N-alpha (9-Fluorenylmethyloxycarbonyl)-N-alpha-(4,5-dimethoxy-2-nitrobenzyl)-glycine
- Product code:FAA7350
- CAS No.:850859-64-2
- Formula:C26H24N2O8
- Storage temperature:2-8°C
- Molecular weight:492.48 g/mol
from €1,000.00
description
Tag for internal solubilization, which can be cleaved by photolysis (350 nm) under ambient conditions. See also our product Fmoc-L-Cys(oNv)-OH (FAA3970), where o-nitroveratryl has been used for thiol protection.
This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis.
references
Synthesis, stability and optimized photolytic cleavage of 4-methoxy-2-nitrobenzyl backbone-protected peptides. Erik C. B. Johnson and Stephen B. H. Kent; Chem. Commun. 2006;
1557-1559. DOI: 10.1039/b600304d
Photomodulation of Protein Trans-Splicing Through Backbone Photocaging of the DnaE Split Intein; Luis Berrade, Youngeun Kwon, and Julio A. Camarero; ChemBioChem 2010; 11: 1368 -
1372. DOI: 10.1002/cbic.201000157
Karas J.A., Scanlon D.B., Forbes B.E., Vetter I., Lewis R.J., Gardiner J., Separovic F., Wade J.D., Hossain M.A.; 2-Nitroveratryl as a Photocleavable Thiol-Protecting Group for
Directed Disulfide Bond Formation in the Chemical Synthesis of Insulin; Chem. Eur. J. 2014; 20: 9549-9552. DOI: 10.1002/chem.201403574.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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