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H-Aeg-OH
Chemical name: N-(2-Aminoethyl)glycine // Synonyms: N-beta-Aminoethyl-Gly-OH, Ethylenediamine-N-monoacetic acid, 2-[(2-aminoethyl)amino]acetic acid, Aminoethyl-glycine
- Product code:HAA9200
- CAS No.:24123-14-6
- Formula:C4H10N2O2
- Storage temperature:2-8°C
- Molecular weight:118.14 g/mol
- Purity :min. 99%
from €78.00
description
Functional building block for the synthesis of peptide nucleic acids and a variety of other reactions, e.g. peptidomimetics, linker with branching functionality. Iris Biotech also offers the Fmoc-protected derivative H-Aeg(Fmoc)-OH*HCl (HAA3180) as well as the double protected Boc-Aeg(Fmoc)-OH (BAA2980) and Fmoc-Aeg(Boc)-OH (FAA1767).
This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis.
references
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules; M. Egholm, O. Buchardt, L. Christensen, C. Behrens, S. M. Freier, D. A. Driver, R. H. Berg, S. K. Kim, B. Norden, P. E. Nielsen; Nature 1993; 365: 566-568. https://doi.org/10.1038/365566a0.
Peptide nucleic acids rather than RNA may have been the first genetic molecule; K. E. Nelson; M. Levy; S. L. Miller; PNAS 2000; 97(8): 3868-3871. https://doi.org/10.1073/pnas.97.8.3868.
Encoded combinatorial peptide libraries containing non-natural amino acids; J. M. Kerr, S. C. Banville, R. N. Zuckermann; J. Am. Chem. Soc. 1993; 115(6): 2529-2531. https://doi.org/10.1021/ja00059a070.
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